Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31581214 | 0.81 | TLR8 (0.47) | TLR8TLR7 | |
| SCHEMBL5766447 | 0.75 | TLR8 (0.46) | TLR8TLR7POLB | |
| SCHEMBL5146757 | 0.72 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL5090110 | 0.69 | CA12 (0.41) | TLR8TLR7 | |
| SCHEMBL5790821 | 0.68 | TLR8 (0.50) | TLR8TLR7POLB | |
| SCHEMBL1527960 | 0.68 | TLR8 (0.67) | TLR8TLR7 | |
| SCHEMBL5765345 | 0.68 | TLR8 (0.48) | TLR8TLR7POLB | |
| SCHEMBL15920638 | 0.68 | POLB (0.59) | TLR8TLR7POLB | |
| SCHEMBL5095437 | 0.66 | CA1 (0.33) | TLR8TLR7 | |
| SCHEMBL31581157 | 0.64 | TLR8 (0.59) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110929-A | IMMUNOMODULATORS WHICH INDUCE CYTOKINE BIOSYNTHESIS, INCLUDING INTERFERON AND/OR TUMOR BIOSYNTHESIS, NECROSIS FACTOR AND INHIBIT T-HELPER-TYPE 2 IMMUNE RESPONSE; FOR TREATMENT OF VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-29 | — | — | US | disclosed |