Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 10/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.60 |
| ▸ | MTOR | P42345 | 5/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790128 | 0.94 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL10277872 | 0.87 | PIK3CG (0.60) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL791563 | 0.84 | PIK3CG (0.79) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789701 | 0.83 | PIK3CG (0.73) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807042 | 0.83 | PI4KA (0.74) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807277 | 0.82 | PIK3CA (0.60) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807468 | 0.81 | PIK3CG (0.71) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807274 | 0.81 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807458 | 0.81 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL806732 | 0.79 | PI4KA (0.68) | PI4KAPIK3CGPIK3CAMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |