Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076546 | 1.00 | TAAR1 (0.47) | TAAR1USP2ALDH1A1HPGDTDP1 | |
| SCHEMBL8062063 | 1.00 | TAAR1 (0.47) | TAAR1USP2ALDH1A1HPGDTDP1 | |
| SCHEMBL8072572 | 1.00 | TAAR1 (0.47) | TAAR1USP2ALDH1A1HPGDTDP1 | |
| SCHEMBL248775 | 0.98 | TAAR1 (0.48) | TAAR1USP2ALDH1A1HPGDTDP1 | |
| SCHEMBL8076090 | 0.92 | TAAR1 (0.50) | TAAR1ALDH1A1CHRM2IDO1PNMT | |
| SCHEMBL30462202 | 0.92 | TAAR1 (0.50) | TAAR1ALDH1A1CHRM2IDO1PNMT | |
| SCHEMBL248652 | 0.84 | TAAR1 (0.54) | TAAR1ALDH1A1IDO1PNMTSLC6A2 | |
| SCHEMBL1822278 | 0.84 | TAAR1 (0.62) | TAAR1CHRM2IDO1PNMTSLC6A2 | |
| SCHEMBL5535994 | 0.81 | TAAR1 (0.47) | TAAR1CHRM2IDO1PNMTSLC6A2 | |
| SCHEMBL5541608 | 0.79 | TAAR1 (0.48) | TAAR1CHRM2IDO1PNMTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |