Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.76 |
| ▸ | PI4KA | P42356 | 7/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.58 |
| ▸ | MTOR | P42345 | 6/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277220 | 0.93 | PIK3CG (0.78) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL807153 | 0.93 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL791064 | 0.91 | PIK3CG (0.81) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL807137 | 0.91 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL790765 | 0.90 | PIK3CG (0.74) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL807320 | 0.90 | PIK3CG (0.72) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL807177 | 0.89 | PIK3CG (0.65) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL790865 | 0.88 | PIK3CG (0.79) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL806968 | 0.87 | PIK3CG (0.72) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL807104 | 0.87 | PIK3CG (0.69) | PIK3CGPI4KAPIK3CAMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |