Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 8/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.56 |
| ▸ | MTOR | P42345 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807249 | 0.94 | PIK3CG (0.86) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL807103 | 0.92 | PI4KA (0.76) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL807250 | 0.92 | PI4KA (0.76) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL10277402 | 0.88 | PI4KA (0.76) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL807256 | 0.86 | PIK3CG (0.87) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL807176 | 0.86 | PIK3CG (0.87) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL807085 | 0.86 | PIK3CG (1.00) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL798396 | 0.86 | PIK3CG (0.86) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL789854 | 0.85 | PI4KA (0.72) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL790598 | 0.85 | PIK3CG (0.73) | PI4KAPIK3CGPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |