Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 19/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 18/20 | 0.45 |
| ▸ | GYS1 | P13807 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058230 | 1.00 | HCRTR2 (0.45) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL8067483 | 0.92 | HCRTR2 (0.44) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL15906089 | 0.87 | HCRTR2 (0.47) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL15906091 | 0.87 | HCRTR2 (0.47) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL15906110 | 0.87 | HCRTR2 (0.47) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL13578445 | 0.85 | HCRTR2 (0.45) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL13578446 | 0.85 | HCRTR2 (0.45) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL13578438 | 0.85 | HCRTR2 (0.45) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL8073873 | 0.85 | HCRTR2 (0.39) | HCRTR2HCRTR1GYS1 | |
| SCHEMBL8053607 | 0.85 | HCRTR2 (0.39) | HCRTR2HCRTR1GYS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |