Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP5K1C | O60331 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10210983 | 0.94 | PIP5K1C (0.52) | PIP5K1C | |
| SCHEMBL807342 | 0.94 | PIP5K1C (0.52) | PIP5K1C | |
| Trifluoroacetic Acid SCHEMBL15065443 | 0.89 | PIP5K1C (0.47) | PIP5K1C | |
| SCHEMBL10211062 | 0.88 | PIP5K1C (0.57) | PIP5K1CMAPK1 | |
| SCHEMBL807205 | 0.83 | PIP5K1C (0.51) | PIP5K1CMAPK1 | |
| SCHEMBL806815 | 0.83 | PIP5K1C (0.51) | PIP5K1CMAPK1 | |
| SCHEMBL807469 | 0.83 | PIP5K1C (0.51) | PIP5K1CBRD4CREBBP | |
| SCHEMBL10210906 | 0.80 | MAPK1 (0.58) | MAPK1BRD4CREBBP | |
| SCHEMBL15064704 | 0.79 | BRD4 (0.50) | PIP5K1CBRD4CREBBP | |
| SCHEMBL15064706 | 0.79 | BRD4 (0.50) | PIP5K1CBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |