Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.60 |
| ▸ | CASR | P41180 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072276 | 1.00 | CNR1 (0.60) | CNR1CASRMAPTNPY5RHSD17B10 | |
| SCHEMBL8067598 | 0.89 | CNR1 (0.69) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL8067593 | 0.89 | CNR1 (0.69) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL9125476 | 0.87 | CNR1 (0.61) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL9125482 | 0.87 | CNR1 (0.61) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL8058435 | 0.84 | CNR1 (0.58) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL8058439 | 0.84 | CNR1 (0.58) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL8067595 | 0.84 | CNR1 (0.58) | CNR1CASRMAPTHSD17B10UTS2R | |
| SCHEMBL19195328 | 0.81 | CNR1 (0.88) | CNR1CASRMAPTHSD17B10NPC1 | |
| SCHEMBL8067530 | 0.81 | UTS2R (0.57) | CNR1CASRMAPTUTS2RNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |