SCHEMBL8072337

SCHEMBL8072337

C=CCCCC/C=C(/C)CC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.37
ABCC4 O15439 1/20 0.37
LMNA P02545 2/20 0.36
LSS P48449 1/20 0.34
USP2 O75604 2/20 0.33
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RECQL P46063 1/20 0.33
LPAR3 Q9UBY5 2/20 0.32
ALOX15 P16050 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32
HPGD P15428 1/20 0.32
TRPA1 O75762 2/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL849059 1.00 TSHR (0.48) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL849060 1.00 TSHR (0.48) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL848895 0.98 TSHR (0.52) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL848894 0.98 TSHR (0.52) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL848618 0.95 TSHR (0.46) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL465310 0.95 TSHR (0.46) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL465309 0.95 TSHR (0.46) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL848542 0.85
SCHEMBL848543 0.85
SCHEMBL8072280 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686649-B1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-08-02 EP disclosed
US-5670580-A POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US disclosed
EP-0486293-B1 Thermoplastic resin compositions having improved strength and method for producing them MITSUBISHI CHEM CORP (JP) 1996-04-10 EP disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
US-5229463-A Blending, crosslinking propylene copolymerized with conjugated and non-connugated dienes, EPDM rubber and crystalline propylene polymer MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-07-20 US disclosed
EP-0486293-A2 Thermoplastic resin compositions having improved strength and method for producing them MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-20 EP disclosed