Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.54 |
| ▸ | MTOR | P42345 | 4/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790715 | 0.90 | PIK3CG (0.75) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807169 | 0.89 | PIK3CG (0.74) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807170 | 0.86 | PIK3CG (0.71) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL10277173 | 0.86 | PIK3CG (0.73) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL791064 | 0.86 | PIK3CG (0.81) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789413 | 0.86 | PIK3CG (0.72) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807154 | 0.85 | PIK3CG (0.82) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789386 | 0.85 | PIK3CG (0.82) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807070 | 0.84 | PIK3CG (0.80) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807079 | 0.83 | PI4KA (0.77) | PI4KAPIK3CGPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |