Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499279 | 0.78 | AR (0.58) | ARKCNH2SRD5A2 | |
| SCHEMBL8499041 | 0.77 | AR (0.61) | ARKCNH2SRD5A2 | |
| SCHEMBL13403556 | 0.76 | AR (0.65) | ARKCNH2SRD5A2 | |
| SCHEMBL13403490 | 0.76 | AR (0.64) | ARKCNH2SRD5A2 | |
| SCHEMBL8064193 | 0.75 | AR (0.56) | ARKCNH2SRD5A2 | |
| SCHEMBL13403555 | 0.75 | AR (0.69) | ARKCNH2SRD5A2 | |
| SCHEMBL9546770 | 0.75 | AR (0.68) | ARKCNH2SRD5A2 | |
| SCHEMBL2639362 | 0.75 | AR (0.68) | ARKCNH2SRD5A2 | |
| SCHEMBL4795422 | 0.75 | AR (0.68) | ARKCNH2SRD5A2 | |
| SCHEMBL13403492 | 0.74 | AR (0.67) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641208-B1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 2000-08-02 | — | — | EP | claimed |