SCHEMBL8072914

SCHEMBL8072914

C[Si](N=C=O)(N=C=O)O[Si](C)(N=C=O)N=C=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21929474 0.75 TSHR (0.32) TSHRCASP1
SCHEMBL10432713 0.75
SCHEMBL16198589 0.73
SCHEMBL1048303 0.69
SCHEMBL5463 0.69
SCHEMBL10431190 0.69
SCHEMBL8716070 0.67
SCHEMBL452031 0.67
Methane SCHEMBL13560507 0.65
SCHEMBL7705686 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3180373-B1 BIOMATERIAL WITH REDUCED INFLAMMATORY RESPONSE GOVERNING COUNCIL UNIV TORONTO (CA) 2021-04-07 EP claimed
EP-4702059-A1 N-CADHERIN TARGETING CHIMERIC PEPTIDES FOR INHIBITING RESTENOSIS The Governing Council of the University of Toronto (CA) 2026-03-04 EP disclosed
WO-2024221109-A1 N-CADHERIN TARGETING CHIMERIC PEPTIDES FOR INHIBITING RESTENOSIS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-10-31 WO disclosed
US-10973950-B2 Biomaterial with reduced inflammatory response THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2021-04-13 US disclosed
EP-3180373-B1 BIOMATERIAL WITH REDUCED INFLAMMATORY RESPONSE GOVERNING COUNCIL UNIV TORONTO (CA) 2021-04-07 EP disclosed
US-20170232142-A1 Biomaterial with Reduced Inflammatory Response THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2017-08-17 US disclosed
JP-2000247982-A PRODUCTION OF ISOCYANATODISILOXANE MATSUMOTO SEIYAKU KOGYO KK 2000-09-12 JP disclosed