Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.64 |
| ▸ | PI4KA | P42356 | 4/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.56 |
| ▸ | MTOR | P42345 | 7/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807253 | 0.88 | PIK3CG (0.69) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL12474913 | 0.87 | PIK3CG (0.71) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL807162 | 0.87 | PIK3CG (0.69) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL10277100 | 0.85 | PIK3CG (0.66) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL806801 | 0.85 | PIK3CG (0.65) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL807483 | 0.84 | PIK3CG (0.71) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL790704 | 0.83 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL10277562 | 0.83 | PIK3CG (0.76) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL789789 | 0.83 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAPIK3R1MTOR | |
| SCHEMBL807138 | 0.83 | PIK3CG (0.69) | PIK3CGPI4KAPIK3CAPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |