Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122678 | 0.81 | HTR1D (0.51) | HTR1DKMT2AMEN1ALDH1A1HSD11B1 | |
| SCHEMBL7128499 | 0.77 | KMT2A (0.54) | KMT2AALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL7121410 | 0.76 | KMT2A (0.82) | KMT2AMEN1ALDH1A1HSD17B10MTNR1A | |
| SCHEMBL7129757 | 0.76 | KMT2A (0.82) | KMT2AMEN1ALDH1A1HSD17B10MTNR1A | |
| SCHEMBL7129424 | 0.76 | NPC1 (0.65) | ALDH1A1HSD17B10MTNR1AMTNR1BADRB2 | |
| SCHEMBL8925143 | 0.74 | HTR1D (1.00) | HTR1DHTR1A | |
| SCHEMBL8957615 | 0.73 | HTR1D (0.94) | HTR1DHTR1A | |
| SCHEMBL6085448 | 0.72 | SMN1; SMN2 (0.54) | KMT2AMEN1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11740707 | 0.72 | SMN1; SMN2 (0.73) | KMT2AMEN1ALDH1A1HSD11B1LMNA | |
| SCHEMBL12218242 | 0.71 | HPGD (0.68) | KMT2AMEN1ALDH1A1HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820434-B1 | PHENOXYETHYLAMINE DERIVATIVES HAVING HIGH AFFINITY FOR THE 5-HT 1A RECEPTOR, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SOD CONSEILS RECH APPLIC (FR) | 2000-08-09 | — | — | EP | disclosed |