SCHEMBL8073268

SCHEMBL8073268

C#CC/C(C(=O)O)=C(\CC#C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.31
MCL1 Q07820 1/20 0.30
GRIK1 P39086 2/20 0.30
GRIK2 Q13002 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10767020 1.00 CYP1A2 (0.35) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL10767023 1.00 CYP1A2 (0.35) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL9358639 0.81
SCHEMBL9358635 0.81
SCHEMBL15515930 0.73 FNTA (0.38) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL8166479 0.73 CYP2D6 (0.46) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL8166475 0.73 CYP2D6 (0.46) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL31046 0.72
SCHEMBL9947552 0.71 KDM4E (0.31) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1004562 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115243876-A Method for producing coextruded cross-linked polyolefin foams with polyamide covering layer 东丽塑料美国股份有限公司 2022-10-25 CN disclosed
CN-115243877-A Co-extruded crosslinked multilayer polyolefin foam structure with crosslinked polyolefin cover layer, and method for making same 东丽塑料美国股份有限公司 2022-10-25 CN disclosed
CN-115243878-A Co-extruded cross-linked polyolefin foam with polyamide cover layer 东丽塑料美国股份有限公司 2022-10-25 CN disclosed
EP-0273274-B1 Degradation of polyethylene by means of agents generating free radicals ATOCHEM ELF DEUTSCHLAND (DE) 2000-07-12 EP disclosed
EP-0444604-A2 Crosslinking of fluorrubber via crosslinking initiators not forming any methyl- or phenyl-radicals Elf Atochem Deutschland GmbH (DE) 1991-09-04 EP disclosed
EP-0180789-B1 CROSS-LINKING OF STYRENE POLYMERS Luperox GmbH (DE) 1990-02-28 EP disclosed
US-4638019-A OLIGOMERIC MALEIC ACID ESTER ENDCAPPED WITH UNSATURATED ALCOHOL, PROMOTERS SIEMENS AKTIENGESELLSCHAFT (DE) 1987-01-20 US disclosed
EP-0180789-A1 Cross-linking of styrene polymers Luperox GmbH (DE) 1986-05-14 EP disclosed
EP-0073038-B1 PROCESS FOR CROSS-LINKING AND IF REQUIRED FOAMING NATURAL OR SYNTHETIC HOMO- AND/OR COPOLYMERS Luperox GmbH (DE) 1986-01-02 EP disclosed
EP-0073038-A1 Process for cross-linking and if required foaming natural or synthetic homo- and/or copolymers Luperox GmbH (DE) 1983-03-02 EP disclosed