SCHEMBL807372

SCHEMBL807372

Nc1ccc2c(c1)OCCOCCOc1ccc(N)cc1OCCOCCO2

nearest known ligand 0.96

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.96
KDM4E B2RXH2 3/20 0.96
GAA P10253 1/20 0.96
LMNA P02545 4/20 0.59
HTT P42858 2/20 0.59
BLM P54132 1/20 0.59
CRHBP P24387 2/20 0.54
CRHR2 Q13324 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
KMT2A Q03164 1/20 0.47
PKM P14618 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TSHR P16473 1/20 0.46
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16773127 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL31474896 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL31617079 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL31038567 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL19054921 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL16772950 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL1247271 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL1247565 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL22387084 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT
SCHEMBL15533415 1.00 MAPT (0.96) MAPTKDM4EGAALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200277441-A1 TROGER'S BASE-LINKED POLY(CROWN ETHERS)S NORTHWESTERN UNIVERSITY 2020-09-03 US disclosed
EP-2616493-B1 POLYMERISATION METHOD UNIV COURT UNIV OF EDINBURGH (GB) 2020-07-01 EP disclosed
WO-2017111117-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 2017-06-29 WO disclosed
US-9018270-B2 Method for producing polymers comprising multiple repeat units of bicyclic diamines UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2015-04-28 US disclosed
US-9018270-B2 Method for producing polymers comprising multiple repeat units of bicyclic diamines UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2015-04-28 US disclosed
US-20130267616-A1 Polymerisation Method UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-10-10 US disclosed
US-20130267616-A1 Polymerisation Method UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-10-10 US disclosed
WO-2012035327-A1 POLYMERISATION METHOD UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-03-22 WO disclosed
US-7390863-B2 Polymeric materials having enhanced ion and water transport property and medical devices comprising same BAUSCH & LOMB INCORPORATED (US) 2008-06-24 US disclosed
US-7390863-B2 Polymeric materials having enhanced ion and water transport property and medical devices comprising same BAUSCH & LOMB INCORPORATED (US) 2008-06-24 US disclosed
US-20070049713-A1 Polymeric materials having enhanced ion and water transport property and medical devices comprising same BAUSCH & LOMB INCORPORATED 2007-03-01 US disclosed
US-20070049713-A1 Polymeric materials having enhanced ion and water transport property and medical devices comprising same BAUSCH & LOMB INCORPORATED 2007-03-01 US disclosed