Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 7/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073865 | 1.00 | SRD5A2 (0.63) | SRD5A2ARKCNH2 | |
| SCHEMBL8063856 | 0.88 | AR (0.61) | SRD5A2ARKCNH2 | |
| SCHEMBL8076925 | 0.88 | AR (0.61) | SRD5A2ARKCNH2 | |
| SCHEMBL8063860 | 0.88 | AR (0.61) | SRD5A2ARKCNH2 | |
| SCHEMBL8077641 | 0.86 | AR (0.61) | SRD5A2ARKCNH2 | |
| SCHEMBL8077639 | 0.86 | AR (0.61) | SRD5A2ARKCNH2 | |
| SCHEMBL8495924 | 0.85 | AR (0.63) | SRD5A2ARKCNH2 | |
| SCHEMBL8495920 | 0.85 | AR (0.63) | SRD5A2ARKCNH2 | |
| SCHEMBL8496657 | 0.85 | AR (0.63) | SRD5A2ARKCNH2 | |
| SCHEMBL8496662 | 0.85 | AR (0.63) | SRD5A2ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641208-B1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 2000-08-02 | — | — | EP | claimed |
| US-5620986-A | TREATS BENIGN PROSTATIC HYPERTROPHY, SEBORRHEA, FEMALE HIRSUTISM, AND MALE AND FEMALE PATTEN BALDNESS | MERCK & CO., INC. (US) | 1997-04-15 | — | — | US | claimed |