Thiourea

Thiourea

SCHEMBL8073928

C1CCC1.NC(N)=S

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL10771868 1.00
Cyclohexane SCHEMBL1531431 0.84 TSHR (0.46)
Cyclohexane SCHEMBL3051193 0.84 TSHR (0.46)
Cyclopropane SCHEMBL9026881 0.84
Cyclohexane SCHEMBL6972653 0.84 TSHR (0.46)
Thiourea SCHEMBL1008 0.82
Thiourea SCHEMBL30536978 0.82
Thiourea SCHEMBL850383 0.82
Thiourea SCHEMBL30536984 0.82
Cyclopentane SCHEMBL9416374 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114465-A POLYCHLOROPRENE SILANIZED WITH AMORPHOUS SILICA FILLER AND AN ACID ACCEPTOR USING A SILANIZING AGENT PRIOR TO ADDING TO RUBBER OTHER ADDITIVES PAGUAG GMBH & CO. (DE) 2000-09-05 US disclosed
US-4645810-A BLEND OF ACRYLIC ESTER, FREE RADICAL INITIATOR, A THIOUREA AND DIBASIC ORGANIC ACID USM CORPORATION (US) 1987-02-24 US disclosed
US-4447337-A WITH MOLYBDENUM COMPOUND AND A THIOUREA MONSANTO COMPANY (US) 1984-05-08 US disclosed
US-4096201-A BUTADIENE-ACRYLONITRILE COPOLYMER, HYDROXYALKYL METHACRYLATE, ALKYL METHACRYLATE, ORGANIC HYDROPEROXIDE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1978-06-20 US disclosed