Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436025 | 1.00 | MAPK1 (0.67) | MAPK1RARBTP53TSHRPLA2G4B | |
| Hydrochloric Acid SCHEMBL9812237 | 0.98 | MAPK1 (0.65) | MAPK1RARBTP53TSHRPLA2G4B | |
| Hydrochloric Acid SCHEMBL9812242 | 0.98 | MAPK1 (0.65) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL9711933 | 0.94 | TP53 (0.68) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL9515560 | 0.94 | TP53 (0.68) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL21172247 | 0.92 | MAPK1 (0.73) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL8990095 | 0.92 | MAPK1 (0.57) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL8990098 | 0.92 | MAPK1 (0.57) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL10415543 | 0.89 | MAPK1 (0.65) | MAPK1RARBTP53TSHRPLA2G4B | |
| SCHEMBL9868849 | 0.89 | TP53 (0.69) | MAPK1RARBTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7324051-A | — | — | None | — | — | JP | disclosed |
| EP-0646636-B1 | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING & MFG (US) | 2000-08-23 | — | — | EP | disclosed |
| US-6008401-A | CONDENSATION REACTION BETWEEN 4-HALO OR NITRO SUBSTITUTED BENZONITRILE DERIVATIVE AND OTICALLY ACTIVE ALCOHOL PRODUCES AN OPTICALLY ACTIVE ALKOXYBENZONITRILE DERIVATIVE | NIPPON OIL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |
| EP-0425304-B1 | Liquid crystal device with grey scale | MINNESOTA MINING & MFG (US) | 1996-07-17 | — | — | EP | disclosed |
| US-5474705-A | Electrooptical displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| JP-H07324051-A | FLUORINE-CONTAINING CHIRAL SMECTIC LIQUID CRYSTAL | MINNESOTA MINING & MFG CO <3M> | 1995-12-12 | — | — | JP | disclosed |
| EP-0646636-A1 | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5399291-A | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5399701-A | Polyfluoroalkyloxypyridinecarboxylic acid and -carboxaldehyde intermediates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0255236-B1 | Fluorine-containing chiral smectic liquid crystals | MINNESOTA MINING & MFG (US) | 1994-05-04 | — | — | EP | disclosed |
| US-5254747-A | Fluorine-containing chiral smectic liquid crystals | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| US-5100577-A | FERROELECTRIC LIQUID CRYSTAL MIXTURES AND COMPOUNDS AS WELL AS ELECTRO-OPTICAL DEVICES EMPLOYING SAME | HOFFMAN-LA ROCHE INC. (US) | 1992-03-31 | — | — | US | disclosed |
| US-5062691-A | Liquid crystal device with grey scale | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0225728-B1 | LIQUID CRYSTALLINE CARBONIC ACID ESTER AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0425304-A2 | Liquid crystal device with grey scale | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-05-02 | — | — | EP | disclosed |
| US-4886619-A | TILTED OR LATENT TILTED MESOPHASES; BLENDS; FERROELECTRIC DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| US-4759869-A | Carbonic acid ester containing assymetrical carbon atom and benzene rings | CHISSO CORPORATION (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0255236-A2 | Fluorine-containing chiral smectic liquid crystals | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |
| EP-0225728-A2 | Liquid crystalline carbonic acid ester and liquid crystal composition containing same | Chisso Corporation (JP) | 1987-06-16 | — | — | EP | disclosed |