Pyridine

Pyridine

SCHEMBL8074261

O=S(=O)(O)CCBr.c1ccncc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PTGS1 P23219 1/20 0.32
PDE4A P27815 1/20 0.32
LMNA P02545 1/20 0.32
SLC6A6 P31641 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27571173 0.86 NAPRT (0.47) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL27571171 0.86 NAPRT (0.47) NAPRTTSHRTDP1PTGS1PDE4A
Eprodisate SCHEMBL6114796 0.82 NAPRT (0.43) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL6114570 0.82 NAPRT (0.43) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL27883487 0.82 NAPRT (0.43) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL6114284 0.80 NAPRT (0.41) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL28330706 0.80 NAPRT (0.41) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL6114870 0.80 NAPRT (0.41) NAPRTTSHRTDP1PTGS1PDE4A
Pyridine SCHEMBL4849896 0.78 NAPRT (0.39) NAPRTTSHRTDP1PTGS1PDE4A
2-Mercaptoethanesulfonic Acid SCHEMBL9452101 0.78 PTGS1 (0.61) NAPRTTSHRTDP1PTGS1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625726-B1 Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO LTD (JP) 2000-08-09 EP disclosed
US-5616456-A CONTAINIG A MEROCYANINE DYE; HIGH SENSITIVITY, CONTRAST, AND GOOD STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-04-01 US disclosed
US-5439789-A Support having atleast one light sensitive silver halide emulsion layer and methine dye having benzoxazole nucleus with a halogen substituted benzene ring at 5-position FUJI PHOTO FILM CO., LTD. (JP) 1995-08-08 US disclosed
EP-0625726-A1 Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1994-11-23 EP disclosed