Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 15/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068945 | 0.85 | OPRL1 (0.51) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8075771 | 0.84 | OPRL1 (0.37) | OPRL1EGLN1 | |
| SCHEMBL8070777 | 0.83 | EGLN1 (0.52) | OPRL1EGLN1 | |
| SCHEMBL8071080 | 0.83 | EGLN1 (0.52) | OPRL1EGLN1 | |
| SCHEMBL8069366 | 0.82 | OPRL1 (0.66) | OPRL1EGLN1ALDH1A1 | |
| SCHEMBL8074019 | 0.82 | OPRL1 (0.44) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8069092 | 0.81 | OPRL1 (0.57) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8070730 | 0.80 | OPRL1 (0.47) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8071093 | 0.80 | OPRL1 (0.44) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8074024 | 0.79 | OPRL1 (0.40) | OPRL1EGLN1FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |