SCHEMBL8074609

SCHEMBL8074609

COC(OC(N)=O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.75
SRC P12931 1/20 0.44
MAPT P10636 4/20 0.41
KMT2A Q03164 1/20 0.41
KCNN4 O15554 1/20 0.40
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 3/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP2C19 P33261 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PARP1 P09874 2/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
TNF P01375 1/20 0.36
KLF5 Q13887 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5892088 0.87 CES1 (0.80) CES1SRCMAPTKMT2AKCNN4
SCHEMBL1679763 0.86 CES1 (1.00) CES1SRCMAPTKMT2AKCNN4
SCHEMBL15173 0.86 CES1 (1.00) CES1SRCMAPTKMT2AKCNN4
Methoxymethane SCHEMBL28719477 0.84 CES1 (0.96) CES1SRCMAPTKMT2AKCNN4
Formaldehyde SCHEMBL28114609 0.83 CES1 (0.93) CES1SRCMAPTKMT2AKCNN4
SCHEMBL28324796 0.83 CES1 (0.93) CES1SRCMAPTKMT2AKCNN4
Formaldehyde SCHEMBL1128921 0.83 CES1 (0.93) CES1SRCMAPTKMT2AKCNN4
Carbamic Acid SCHEMBL17186652 0.83 CES1 (0.73) CES1SRCMAPTKMT2AKCNN4
Benzil SCHEMBL28623198 0.81 CES1 (0.89) CES1SRCKCNN4TSHRCYP2C19
Benzophenone SCHEMBL20610475 0.81 CES1 (0.89) CES1SRCMAPTKMT2AKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1021159-A1 PHOTORESPONSIVE SUNSCREEN COMPOSITIONS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-07-26 EP disclosed
WO-1999007336-A1 PHOTORESPONSIVE SUNSCREEN COMPOSITIONS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1999-02-18 WO disclosed