Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10212328 | 0.90 | BRD4 (0.60) | BRD4CREBBPMAPK1 | |
| SCHEMBL15065253 | 0.88 | BRD4 (0.60) | BRD4CREBBPMAPK1 | |
| SCHEMBL807436 | 0.88 | BRD4 (0.60) | BRD4CREBBPMAPK1 | |
| SCHEMBL807435 | 0.87 | BRD4 (0.59) | BRD4CREBBPMAPK1 | |
| SCHEMBL807239 | 0.87 | BRD4 (0.64) | BRD4CREBBPMAPK1 | |
| SCHEMBL15082126 | 0.85 | BRD4 (0.57) | BRD4CREBBPMAPK1 | |
| SCHEMBL807221 | 0.85 | BRD4 (0.58) | BRD4CREBBPMAPK1 | |
| SCHEMBL807242 | 0.84 | BRD4 (0.57) | BRD4CREBBPMAPK1 | |
| SCHEMBL807232 | 0.83 | BRD4 (0.67) | BRD4CREBBPMAPK1 | |
| SCHEMBL807225 | 0.83 | BRD4 (0.61) | BRD4CREBBPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |