Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.61 |
| ▸ | AGXT | P21549 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795848 | 1.00 | IDO1 (0.61) | IDO1AGXTCA1CA2APP | |
| SCHEMBL5795851 | 1.00 | IDO1 (0.61) | IDO1AGXTCA1CA2APP | |
| SCHEMBL29302281 | 0.93 | IDO1 (0.53) | IDO1AGXTCA1CA2APP | |
| SCHEMBL1030380 | 0.91 | IDO1 (0.52) | IDO1AGXTCA1CA2APP | |
| SCHEMBL1030381 | 0.91 | IDO1 (0.52) | IDO1AGXTCA1CA2APP | |
| SCHEMBL22468781 | 0.90 | IDO1 (0.55) | IDO1AGXTCA1CA2APP | |
| SCHEMBL22468782 | 0.90 | IDO1 (0.55) | IDO1AGXTCA1CA2APP | |
| SCHEMBL22485576 | 0.90 | IDO1 (0.55) | IDO1AGXTCA1CA2APP | |
| SCHEMBL21835991 | 0.87 | IDO1 (0.52) | IDO1AGXTCA1CA2ALDH1A1 | |
| SCHEMBL21835990 | 0.87 | IDO1 (0.52) | IDO1AGXTCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030733-A1 | METHOD FOR THE SYNTHESIS OF 4-ALKOXY-, 4-HYDROXY- AND 4-ARYLOXY-SUBSTITUTED TETRAHYDRO-FURO[3,4-B]FURAN-2(3H)-ONE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2009-03-12 | — | — | WO | disclosed |