Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322088 | 0.81 | MAOB (0.65) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL9521289 | 0.81 | MAOB (0.48) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL7124438 | 0.79 | MAOB (0.46) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL7070788 | 0.79 | MAOB (0.46) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL7923061 | 0.78 | MAOB (0.45) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL7603176 | 0.75 | CYP1A2 (0.37) | MAOBALDH1A1LMNACYP19A1MAOA | |
| SCHEMBL88390 | 0.74 | MAOB (0.54) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL144447 | 0.73 | MAOB (0.59) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL9790648 | 0.73 | MAOB (0.59) | MAOBMAPK1TRPA1ALDH1A1LMNA | |
| SCHEMBL11374370 | 0.71 | MAOB (0.64) | MAOBMAPK1TRPA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000256289-A | PRODUCTION OF AMINO ACID DERIVATIVE | SUMITOMO CHEM CO LTD | 2000-09-19 | — | — | JP | disclosed |