Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544397 | 0.90 | — | — | |
| Fluoride SCHEMBL895616 | 0.87 | CA9 (0.42) | MAPTALDH1A1MEN1GAAKMT2A | |
| Fluoride SCHEMBL944796 | 0.87 | CA9 (0.42) | MAPTALDH1A1MEN1GAAKMT2A | |
| Fluoride SCHEMBL944793 | 0.87 | CA9 (0.42) | MAPTALDH1A1MEN1GAAKMT2A | |
| Fluoride SCHEMBL895619 | 0.87 | CA9 (0.42) | MAPTALDH1A1MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL945329 | 0.84 | CA9 (0.40) | MAPTALDH1A1MEN1GAAKMT2A | |
| SCHEMBL8511695 | 0.83 | ESR1 (0.39) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10300262 | 0.83 | BCL2L1 (0.55) | BCL2L1BADMAPTMAOBNPC1 | |
| SCHEMBL10337645 | 0.83 | BCL2L1 (0.55) | BCL2L1BADMAPTMAOBNPC1 | |
| SCHEMBL197346 | 0.83 | BCL2L1 (0.55) | BCL2L1BADMAPTMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110964-A | FOR TREATING ARTHRITIS, INFLAMMATORY BOWEL DISEASE, CROHN'S DISEASE, EMPHYSEMA, ACUTE RESPIRATORY DISTRESS SYNDROME, ASTHMA CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ALZHEIMER'S DISEASE, ORGAN TRANSPLANT TOXICITY, CACHEXIA, CANCER | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |