Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807491 | 0.83 | — | — | |
| SCHEMBL806815 | 0.82 | PIP5K1C (0.51) | PIP5K1C | |
| SCHEMBL807205 | 0.82 | PIP5K1C (0.51) | PIP5K1C | |
| SCHEMBL806918 | 0.81 | — | — | |
| SCHEMBL15065444 | 0.81 | MAPK1 (0.43) | PIP5K1C | |
| SCHEMBL15065440 | 0.81 | MAPK1 (0.43) | PIP5K1C | |
| SCHEMBL10210846 | 0.81 | MAPK1 (0.43) | PIP5K1C | |
| SCHEMBL15065442 | 0.81 | MAPK1 (0.43) | PIP5K1C | |
| SCHEMBL807485 | 0.79 | — | — | |
| SCHEMBL15065585 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |