Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114367 | 0.96 | NPC1 (0.79) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL584234 | 0.94 | NPC1 (0.71) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL7683393 | 0.94 | NPC1 (0.71) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL11170918 | 0.92 | NPC1 (0.74) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL584503 | 0.92 | NPC1 (0.69) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL13144461 | 0.92 | NPC1 (0.73) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL5095881 | 0.90 | NPC1 (0.71) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL584156 | 0.89 | NPC1 (0.66) | NPC1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL91308 | 0.89 | NPC1 (1.00) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL3266105 | 0.89 | NPC1 (0.69) | NPC1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292142-A | MIXTURE OF PHTHALIC ANHYDRIDE AND MALEIC ANHYDRIDE | INTERNATIONAL SYNTHETIC RUBBER CO., LTD. (GB) | 1981-09-29 | — | — | US | claimed |
| CN-1314659-C | Method for preparing ioxitalamic acid | JIANGSU INST OF NUCLEAR MED (CN) | 2007-05-09 | — | — | CN | disclosed |
| CN-1803765-A | Method for preparing ioxitalamic acid | JIANGSU INST OF NUCLEAR MED (CN) | 2006-07-19 | — | — | CN | disclosed |
| EP-0879815-B1 | Process for the preparation of the 5-nitro-isophthalic-di- C1-C4-alkyl esters | BAYER AG (DE) | 2000-11-02 | — | — | EP | disclosed |
| US-6002041-A | Process for preparing di-C1 - C4 -alkyl 5-nitro-isophthalates | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0879815-A1 | Process for the preparation of the 5-nitro-isophthalic-di- C1-C4-alkyl esters | BAYER AG (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1993023352-A1 | NITRATION SYSTEM, AND PROCESS FOR NITRATING AROMATIC COMPOUNDS | NORSK HYDRO A.S (NO) | 1993-11-25 | — | — | WO | disclosed |
| EP-0203957-B1 | 5-(3,5-DISUBSTITUTED PHENYLAZO)-2-HYDROXYBENZENE ACETIC ACIDS AND SALTS AND LACTONES THEREOF, AND PHARMACEUTICAL COMPOSITIONS OF SAID ACIDS, SALTS, AND LACTONES | PHARMACIA AB (SE) | 1990-03-14 | — | — | EP | disclosed |
| US-4725676-A | 5-(3,5-disubstituted phenylazo)-2-hydroxybenzene-acetic acids and salts and lactones thereof having a potentially inhibitory effect on 15-hydroxy-prostaglandin dehydrogenase | PHARMACIA AB (SE) | 1988-02-16 | — | — | US | disclosed |
| EP-0203957-A1 | 5-(3,5-disubstituted phenylazo)-2-hydroxybenzene acetic acids and salts and lactones thereof, and pharmaceutical compositions of said acids, salts, and lactones. | PHARMACIA AB (SE) | 1986-12-10 | — | — | EP | disclosed |
| WO-1986003195-A1 | NOVEL AZO COMPOUNDS | PHARMACIA AB (SE) | 1986-06-05 | — | — | WO | disclosed |