Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000973 | 1.00 | KDM4E (0.42) | KDM4EPKMHTR2CSLC6A4NAMPT | |
| SCHEMBL2022224 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL2023544 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL7988112 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL2024498 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL2025069 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL7992205 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL2025474 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL2025373 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL8001005 | 0.86 | SYK (0.43) | ALDH1A1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156817-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |