Triclocarban

Triclocarban

SCHEMBL8076465

O=C(Nc1ccc(Cl)cc1)Nc1ccc(Cl)c(Cl)c1.Oc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.79
MEN1 O00255 4/20 0.79
KMT2A Q03164 4/20 0.79
HTT P42858 3/20 0.79
EPHX1 P07099 2/20 0.79
EPHX2 P34913 2/20 0.79
LMNA P02545 2/20 0.79
ADORA3 P0DMS8 1/20 0.79
CHRM1 P11229 1/20 0.79
SLC6A2 P23975 1/20 0.79
PDE4A P27815 1/20 0.79
ADRA1A P35348 1/20 0.79
OPRM1 P35372 1/20 0.79
PDE3A Q14432 1/20 0.79
NLRP3 Q96P20 1/20 0.79
CNR1 P21554 5/20 0.63
MAPT P10636 3/20 0.63
RAB9A P51151 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
KDM4E B2RXH2 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triclocarban SCHEMBL27313500 0.89 MEN1 (1.00) NPC1MEN1KMT2AHTTEPHX1
Triclocarban SCHEMBL30479188 0.89 MEN1 (1.00) NPC1MEN1KMT2AHTTEPHX1
Triclocarban SCHEMBL4978963 0.89 MEN1 (1.00) NPC1MEN1KMT2AHTTEPHX1
Triclocarban SCHEMBL68658 0.89 MEN1 (1.00) NPC1MEN1KMT2AHTTEPHX1
Triclocarban SCHEMBL10888069 0.87 MEN1 (0.96) NPC1MEN1KMT2AHTTEPHX1
SCHEMBL1877660 0.87 EPHX1 (0.81) NPC1MEN1KMT2AHTTEPHX1
SCHEMBL7980937 0.87 EPHX1 (0.81) NPC1MEN1KMT2AHTTEPHX1
SCHEMBL1877761 0.83 EPHX1 (0.73) NPC1MEN1KMT2AHTTEPHX1
Triclocarban SCHEMBL28363580 0.82 NPC1 (0.74) NPC1MEN1KMT2AHTTEPHX1
SCHEMBL2683478 0.82 EPHX1 (1.00) NPC1MEN1KMT2AHTTEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6147120-A APPLYING MIXTURE OF TRICLOSAN, CHLORHEXIDINE DIGLUCONATE, AND ALCOHOL TO HANDS ECOLAB INC. (US) 2000-11-14 US disclosed