SCHEMBL8077079

SCHEMBL8077079

Cc1cccc2c1-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1c(Cl)c(Cl)c(Cl)c(Cl)c41)-c1ccccc1-3)c1ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.34
CYP2D6 P10635 5/20 0.34
CYP3A4 P08684 5/20 0.34
HSD17B10 Q99714 5/20 0.34
CLK4 Q9HAZ1 4/20 0.34
CYP2C19 P33261 3/20 0.34
ALOX15 P16050 2/20 0.34
USP2 O75604 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
APEX1 P27695 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8077083 0.87 TDP1 (0.34) CYP1A2CYP2D6CYP3A4HSD17B10CYP2C19
SCHEMBL7713252 0.87 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CYP2C19
SCHEMBL5197544 0.87 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CLK4
SCHEMBL11786632 0.86 CYP1A2 (0.35) CYP1A2CYP2D6CYP3A4HSD17B10CLK4
SCHEMBL5532913 0.85 TDP1 (0.37) CYP1A2CYP2D6CYP3A4HSD17B10CYP2C19
SCHEMBL5534562 0.85 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CLK4
SCHEMBL11743521 0.85 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CLK4
SCHEMBL11745854 0.85 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CLK4
SCHEMBL11746656 0.85 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CLK4
SCHEMBL498483 0.85 TDP1 (0.38) CYP1A2CYP2D6CYP3A4HSD17B10CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686216-A ORGANIC PHOTOCONDUCTOR LAYER WITH IMPROVED MOISTURE RESISTANCE, POLYESTER BINDER, PHTHALOCYANINE CONDUCTOR, ELECTROGRAPHY MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1997-11-11 US claimed
EP-0738933-B1 Photosensitive member and method of producing the same MITSUBISHI ELECTRIC CORP (JP) 2000-09-06 EP disclosed
US-5686216-A ORGANIC PHOTOCONDUCTOR LAYER WITH IMPROVED MOISTURE RESISTANCE, POLYESTER BINDER, PHTHALOCYANINE CONDUCTOR, ELECTROGRAPHY MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1997-11-11 US disclosed
EP-0738933-A1 Photosensitive member and method of producing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1996-10-23 EP disclosed
EP-0058084-B1 SENSITIZED ELECTROPHOTOGRAPHIC PHOTOSENSITIVE COMPOSITION MITA INDUSTRIAL CO. LTD. (JP) 1985-05-08 EP disclosed
US-4419429-A PHTHALOCYANINE, NITROPHTHALIC ANHYDRIDE MITA INDUSTRIAL CO., LTD. (JP) 1983-12-06 US disclosed
EP-0058084-A1 Sensitized electrophotographic photosensitive composition MITA INDUSTRIAL CO. LTD. (JP) 1982-08-18 EP disclosed
US-4226928-A PHTHALOCYANINE LAYER, AROMATIC NITRO COMPOUND, POLYVINYLCARBAZOLE PHOTOCONDUCTOR MITA INDUSTRIAL COMPANY, LTD. (JP) 1980-10-07 US disclosed
US-4214907-A Photosensitive material for electrophotography having a polyvinyl carbazole derivative, phthalocyanine, and an electron-acceptor MITA INDUSTRIAL COMPANY, LTD. (JP) 1980-07-29 US disclosed
US-4106935-A Xerographic plate having an phthalocyanine pigment interface barrier layer XEROX CORPORATION (US) 1978-08-15 US disclosed