SCHEMBL8077205

SCHEMBL8077205

C=CCCC(C)=C(C)CC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
ALDH1A1 P00352 3/20 0.38
LSS P48449 1/20 0.32
LMNA P02545 1/20 0.30
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8077204 1.00 TSHR (0.41) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL8767066 0.89 TSHR (0.42) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL8767061 0.89 TSHR (0.42) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL4930758 0.85 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL4930761 0.85 TSHR (0.46) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL8071927 0.84 TSHR (0.48) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL8071926 0.84 TSHR (0.48) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL8679314 0.80 TSHR (0.52) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL8679312 0.80 TSHR (0.52) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL8072332 0.80 TSHR (0.38) TSHRALDH1A1LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686649-B1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-08-02 EP disclosed
US-5670580-A POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US disclosed
EP-0486293-B1 Thermoplastic resin compositions having improved strength and method for producing them MITSUBISHI CHEM CORP (JP) 1996-04-10 EP disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
US-5229463-A Blending, crosslinking propylene copolymerized with conjugated and non-connugated dienes, EPDM rubber and crystalline propylene polymer MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-07-20 US disclosed
EP-0486293-A2 Thermoplastic resin compositions having improved strength and method for producing them MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-20 EP disclosed