Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797937 | 0.87 | KMT2A (0.44) | ACACBCARM1NR1I2UGCGKMT2A | |
| SCHEMBL8077363 | 0.84 | MEN1 (0.44) | ACACBCARM1NR1I2UGCGKMT2A | |
| SCHEMBL7801319 | 0.81 | KMT2A (0.43) | ACACBCARM1NR1I2UGCGKMT2A | |
| SCHEMBL7799922 | 0.81 | KMT2A (0.43) | ACACBCARM1NR1I2UGCGKMT2A | |
| SCHEMBL7802459 | 0.77 | KMT2A (0.43) | CARM1NR1I2UGCGKMT2AMEN1 | |
| SCHEMBL7802393 | 0.77 | KMT2A (0.44) | CARM1NR1I2UGCGKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7791936 | 0.76 | HSD17B10 (0.44) | NR1I2UGCGKMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7797935 | 0.76 | KMT2A (0.43) | CARM1NR1I2UGCGKMT2AMEN1 | |
| SCHEMBL8185612 | 0.76 | KMT2A (0.46) | KMT2AMEN1TSHRCYP3A4MAPT | |
| SCHEMBL7799938 | 0.76 | KMT2A (0.43) | ACACBCARM1NR1I2UGCGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025087-A1 | SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021836-A1 | SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-05-06 | — | — | WO | disclosed |