Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076026 | 0.95 | MAPT (0.50) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL7569153 | 0.94 | MAPT (0.49) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL7563454 | 0.94 | MAPT (0.49) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL7563392 | 0.94 | MAPT (0.49) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL7566970 | 0.94 | MAPT (0.49) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL8075978 | 0.90 | CYP1A2 (0.65) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL8070753 | 0.90 | MAPT (0.54) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL8077689 | 0.85 | CYP1A2 (0.63) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL7563180 | 0.84 | CYP1A2 (0.61) | MAPTCYP1A2CYP3A4TAAR1CALM1 | |
| SCHEMBL7563151 | 0.84 | CYP1A2 (0.61) | MAPTCYP1A2CYP3A4TAAR1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |