Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077683 | 1.00 | AR (0.57) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL8079140 | 0.88 | AR (0.63) | ARSRD5A2KCNH2 | |
| SCHEMBL8079142 | 0.88 | AR (0.63) | ARSRD5A2KCNH2 | |
| SCHEMBL14184873 | 0.84 | AR (0.61) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL2639164 | 0.84 | AR (0.61) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL4799106 | 0.84 | AR (0.61) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL4797509 | 0.84 | AR (0.61) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL8072417 | 0.84 | SRD5A1 (0.58) | SRD5A2SRD5A1 | |
| SCHEMBL8072419 | 0.84 | SRD5A1 (0.58) | SRD5A2SRD5A1 | |
| SCHEMBL8498403 | 0.84 | AR (0.51) | ARSRD5A2KCNH2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641208-B1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 2000-08-02 | — | — | EP | claimed |