SCHEMBL807773

SCHEMBL807773

Cc1cc(Cl)ccc1Oc1ccc(Cl)cc1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 10/20 0.59
SLC6A4 P31645 9/20 0.59
SLC6A3 Q01959 8/20 0.59
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C19 P33261 1/20 0.58
TSHR P16473 1/20 0.52
HTR2A P28223 1/20 0.52
HTR2C P28335 1/20 0.52
HTR2B P41595 1/20 0.52
POLB P06746 2/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KCNH2 Q12809 3/20 0.49
NR1I2 O75469 1/20 0.47
TTR P02766 1/20 0.47
PGR P06401 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13236112 0.91 SLC6A2 (0.60) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL4441083 0.89 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL4434971 0.88 SLC6A4 (0.54) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL15242475 0.88 SLC6A2 (0.67) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL10702984 0.87 CYP1A2 (0.58) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL13749562 0.83 CYP1A2 (0.62) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL91412 0.83 TSHR (0.50) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL13236295 0.82 TTR (0.55) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL10828212 0.82 CYP1A2 (0.49) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL10912813 0.81 TSHR (0.49) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9821493-B2 Microwave dipolar heating of energetic polymers for carbon fiber-matrix separation EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-11-21 US disclosed
US-20160279834-A1 MICROWAVE DIPOLAR HEATING OF ENERGETIC POLYMERS FOR CARBON FIBER-MATRIX SEPARATION CRESTLINE DIRECT FINANCE, L.P. 2016-09-29 US disclosed
US-9394646-B2 Microwave dipolar heating of energetic polymers for carbon fiber-matrix separation EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-07-19 US disclosed
US-20140194645-A1 MICROWAVE DIPOLAR HEATING OF ENERGETIC POLYMERS FOR CARBON FIBER-MATRIX SEPARATION EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-07-10 US disclosed
WO-2014025360-A1 MICROWAVE DIPOLAR HEATING OF ENERGETIC POLYMERS FOR CARBON FIBER-MATRIX SEPARATION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-02-13 WO disclosed
WO-2012035053-A1 COSMETIC COMPOSITION COMPRISING A FIXING POLYMER AND AN ANTIDANDRUFF AGENT L'OREAL (FR) 2012-03-22 WO disclosed