Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052433 | 1.00 | ADRB3 (0.61) | ADRB3ADRB1KDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7052974 | 0.99 | ADRB3 (0.60) | ADRB3ADRB1KDM4ENPC1ALDH1A1 | |
| SCHEMBL7056567 | 0.90 | ADRB3 (0.55) | ADRB3ADRB1PTGDRPTGDR2 | |
| SCHEMBL7056564 | 0.90 | ADRB3 (0.55) | ADRB3ADRB1PTGDRPTGDR2 | |
| SCHEMBL7058076 | 0.87 | ADRB3 (0.68) | ADRB3ADRB1 | |
| SCHEMBL8073362 | 0.87 | ADRB3 (0.68) | ADRB3ADRB1 | |
| SCHEMBL8063475 | 0.86 | ADRB3 (0.57) | ADRB3ADRB1 | |
| SCHEMBL4071040 | 0.86 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL7057571 | 0.86 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL13799337 | 0.86 | ADRB3 (0.67) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069176-A | PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE | MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) | 2000-05-30 | — | — | US | disclosed |