SCHEMBL8078733

SCHEMBL8078733

C[C@@H]1CC(=O)O[C@H](C(C)(C)C)O1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8078738 1.00 SMN1; SMN2 (0.50) SMN1; SMN2CA1CA9
SCHEMBL10717956 0.82 SMN1; SMN2 (0.48) SMN1; SMN2CA1CA9
SCHEMBL22746606 0.73
SCHEMBL804333 0.71 SMN1; SMN2 (0.94) SMN1; SMN2CA1CA9
SCHEMBL22001696 0.71 SMN1; SMN2 (0.94) SMN1; SMN2CA1CA9
SCHEMBL23621134 0.71 SMN1; SMN2 (0.94) SMN1; SMN2CA1CA9
SCHEMBL20582013 0.71 SMN1; SMN2 (0.94) SMN1; SMN2CA1CA9
SCHEMBL9301611 0.71 SMN1; SMN2 (0.94) SMN1; SMN2CA1CA9
SCHEMBL35509 0.69
SCHEMBL432483 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
US-4983766-A Chemical intermediates for optically active secondary alcohols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-08 US disclosed
US-4812476-A SECONDARY ALCOHOLS FROM ALDEHYDE AND 3-HYDROXYBUTYRIC ACID IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-03-14 US disclosed
EP-0244143-A2 Substituted dioxanones and dioxinones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-04 EP disclosed