Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15471796 | 0.86 | CYP17A1 (0.52) | CYP17A1 | |
| SCHEMBL793995 | 0.84 | CYP17A1 (0.52) | CYP17A1 | |
| SCHEMBL793796 | 0.81 | CYP17A1 (0.58) | CYP17A1 | |
| SCHEMBL15471855 | 0.81 | CYP17A1 (0.55) | CYP17A1 | |
| SCHEMBL792837 | 0.77 | CYP17A1 (0.48) | CYP17A1 | |
| SCHEMBL15467436 | 0.77 | CYP17A1 (0.50) | CYP17A1 | |
| SCHEMBL793317 | 0.77 | CYP11B1 (0.57) | CYP17A1 | |
| SCHEMBL793309 | 0.77 | CYP17A1 (0.49) | CYP17A1 | |
| SCHEMBL794363 | 0.77 | CYP17A1 (0.53) | CYP17A1 | |
| SCHEMBL12467223 | 0.77 | CYP17A1 (0.49) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035078-A1 | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |