Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543696 | 1.00 | CACNA1B (0.50) | CACNA1BGNRHR | |
| SCHEMBL7544420 | 0.90 | CACNA1B (0.49) | CACNA1BGNRHR | |
| SCHEMBL7544412 | 0.90 | CACNA1B (0.49) | CACNA1BGNRHR | |
| SCHEMBL7542580 | 0.89 | CACNA1B (0.65) | CACNA1BGNRHR | |
| SCHEMBL7539741 | 0.89 | CACNA1B (0.65) | CACNA1BGNRHR | |
| SCHEMBL7549514 | 0.79 | CACNA1B (0.66) | CACNA1BGNRHR | |
| SCHEMBL7549508 | 0.79 | CACNA1B (0.66) | CACNA1BGNRHR | |
| SCHEMBL7863999 | 0.76 | GNRHR (0.53) | CACNA1BGNRHR | |
| SCHEMBL7863995 | 0.76 | GNRHR (0.53) | CACNA1BGNRHR | |
| SCHEMBL7545829 | 0.73 | CACNA1B (0.73) | CACNA1BGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159989-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 2000-12-12 | — | — | US | disclosed |
| US-6017944-A | TREATING A VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN; PREVENTING PREGNANCY, TREATING LUPUS ERYTHEMATOSIS, IRRITABLE BOWEL SYNDROME, PREMENSTRUAL SYNDROME, HIRSUTISM, SLEEP DISORDERS | MERCK & CO., INC. (US) | 2000-01-25 | — | — | US | disclosed |