Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817863 | 0.77 | USP2 (0.33) | USP2TSHR | |
| SCHEMBL13214756 | 0.77 | USP2 (0.40) | USP2TSHRALDH1A1 | |
| SCHEMBL13214770 | 0.75 | — | — | |
| SCHEMBL13646417 | 0.75 | USP2 (0.32) | USP2TSHR | |
| SCHEMBL777164 | 0.73 | — | — | |
| Phosphonic Acid SCHEMBL8816428 | 0.73 | — | — | |
| SCHEMBL22669105 | 0.73 | USP2 (0.30) | USP2TSHR | |
| SCHEMBL2104398 | 0.69 | USP2 (0.32) | USP2TSHR | |
| SCHEMBL23819874 | 0.69 | — | — | |
| SCHEMBL18373590 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006403-A2 | NON-PEPTIDE MACROCYCLIC HISTONE DEACETYLASE (HDAC) INHIBITORS AND METHODS OF MAKING AND USING THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-08 | — | — | WO | disclosed |