Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748247 | 0.86 | TAAR1 (0.70) | TAAR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3684176 | 0.81 | TAAR1 (0.66) | TAAR1POLB | |
| SCHEMBL8086734 | 0.80 | TAAR1 (0.47) | TAAR1ALDH1A1POLB | |
| SCHEMBL8086177 | 0.77 | RAF1 (0.53) | TAAR1ALDH1A1 | |
| SCHEMBL3643347 | 0.74 | TAAR1 (0.71) | TAAR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3645367 | 0.74 | TAAR1 (0.71) | TAAR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3639447 | 0.74 | TAAR1 (0.68) | TAAR1MEN1KMT2A | |
| SCHEMBL3646208 | 0.74 | TAAR1 (0.68) | TAAR1 | |
| SCHEMBL3643138 | 0.72 | TAAR1 (0.68) | TAAR1 | |
| SCHEMBL3638666 | 0.72 | TAAR1 (0.74) | TAAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |