Lithium Ion

Lithium Ion

SCHEMBL8079692

CC=C(C)[SiH2][O-].[Li+]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675353 0.62
SCHEMBL21383170 0.59
SCHEMBL29024611 0.59
SCHEMBL15208355 0.59
SCHEMBL59867 0.59
SCHEMBL8162015 0.59
SCHEMBL11350790 0.59
SCHEMBL9177019 0.57
SCHEMBL7590806 0.57
SCHEMBL1441474 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679674-B1 Method for preparing diorganopolysiloxane having a functional group at only one end of the molecular chain DOW CORNING TORAY SILICONE (JP) 2000-09-20 EP disclosed
US-5852153-A Trimethylsiloxy group-containing polysiloxane and a process for producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-22 US disclosed
US-5693735-A Trimethylsiloxy group-containing polysiloxane and a process for producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-12-02 US disclosed
EP-0626413-B1 Method for the preparation of diorganopolysiloxanes DOW CORNING TORAY SILICONE (JP) 1997-10-22 EP disclosed
EP-0525782-B1 Process for the preparation of functionalised diphenylsiloxane-dimethylsiloxane copolymers DOW CORNING TORAY SILICONE (JP) 1996-09-04 EP disclosed
US-5486635-A WEATHER AND WATER RESISTANCE DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-01-23 US disclosed
EP-0679674-A2 Method for preparing diorganopolysiloxane having a functional group at only one end of the molecular chain Dow Corning Toray Silicone Company, Limited (JP) 1995-11-02 EP disclosed
US-5399649-A Method for the preparation of diorganopolysiloxanes DOW CORNING TORAY SILICONE CO., LTD. (JP) 1995-03-21 US disclosed
EP-0626413-A2 Method for the preparation of diorganopolysiloxanes Dow Corning Toray Silicone Company, Limited (JP) 1994-11-30 EP disclosed
US-5223596-A DIPHENYSILOXANE-DIMETHYLSIOXANE COPOLYMER AND METHOD FOR THE PREPARATION THEREOF DOW CORNING TORAY SILICONE CO., LTD. (JP) 1993-06-29 US disclosed
US-4948907-A REACTING OCTAORGANOCYCLOTETRASILOXANE WITH LITHIUM SILANOLATE AND ORGANOHALOSILANE WACKER-CHEMIE GMBH (DE) 1990-08-14 US disclosed