SCHEMBL8079737

SCHEMBL8079737

CC(C)(C)c1ccc(OC(=O)c2ccccc2O)cc1.CCCCCCCCc1ccc(OC(=O)c2ccccc2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ESRRG P62508 1/20 0.51
STS P08842 2/20 0.51
THRB P10828 2/20 0.48
THRA P10827 1/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PLK1 P53350 4/20 0.46
KAT8 Q9H7Z6 3/20 0.44
PLK3 Q9H4B4 3/20 0.43
EP300 Q09472 1/20 0.43
KAT5 Q92993 1/20 0.43
PTGS2 P35354 1/20 0.43
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Salicylate SCHEMBL10436750 0.98 HPGD (0.52) MAPTNPSR1ESRRGSTSTHRB
SCHEMBL11705063 0.92 HSD17B10 (0.56) MAPTTHRBTHRAHPGDHSD17B10
SCHEMBL2804130 0.92 HSD17B10 (0.56) MAPTTHRBTHRAHPGDHSD17B10
SCHEMBL78019 0.92 HSD17B10 (0.56) MAPTTHRBTHRAHPGDHSD17B10
SCHEMBL31121312 0.92 HSD17B10 (0.56) MAPTTHRBTHRAHPGDHSD17B10
SCHEMBL9438255 0.92 MAPT (0.48) MAPTNPSR1ESRRGSTSTHRB
SCHEMBL9438258 0.90 PPARA (0.54) ESRRGSTSTHRBTHRAHPGD
SCHEMBL9807232 0.89 NPSR1 (0.53) MAPTNPSR1ESRRGSTSTHRB
SCHEMBL11770527 0.87 KAT8 (0.51) MAPTSTSTHRBTHRAHSD17B10
SCHEMBL410854 0.87 HPGD (0.59) MAPTNPSR1THRBTHRAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678377-B1 Thermochromic laminate PILOT INK CO LTD (JP) 2000-09-20 EP disclosed
US-5688592-A Thermochromic laminate comprising light intercepting pigment and light stabilizer THE PILOT INK CO., LTD. (JP) 1997-11-18 US disclosed