Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | MMP3 | P08254 | 6/20 | 0.40 |
| ▸ | MMP7 | P09237 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966854 | 1.00 | MEN1 (0.48) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL8079850 | 1.00 | MEN1 (0.48) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL4323534 | 0.77 | CYP2C19 (0.45) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL15670960 | 0.75 | KMT2A (0.59) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL15670729 | 0.75 | KMT2A (0.59) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL3333078 | 0.74 | MEN1 (0.39) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL15812399 | 0.73 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL15670940 | 0.73 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL19349131 | 0.73 | MEN1 (0.61) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL1701279 | 0.72 | KMT2A (0.76) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140510-A | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-31 | — | — | US | claimed |
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | claimed |
| US-6140510-A | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| US-5962697-A | Optically active 3-(1-(alkylamino))alkyl pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| US-5773610-A | Optically active 3-(1-(alkylamino))alkyl pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |