⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268922 | 0.70 | — | — | |
| SCHEMBL5504195 | 0.69 | — | — | |
| SCHEMBL11129433 | 0.68 | — | — | |
| SCHEMBL7677663 | 0.67 | DPP4 (0.31) | — | |
| SCHEMBL4751771 | 0.66 | — | — | |
| SCHEMBL4751977 | 0.66 | — | — | |
| SCHEMBL5175708 | 0.65 | UGT2B7 (0.34) | — | |
| SCHEMBL9298809 | 0.65 | — | — | |
| SCHEMBL395882 | 0.64 | — | — | |
| SCHEMBL4749332 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140510-A | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| US-5962697-A | Optically active 3-(1-(alkylamino))alkyl pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| US-5773610-A | Optically active 3-(1-(alkylamino))alkyl pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |