Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079932 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL28162321 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL19667752 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL15688437 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL15688436 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL17682006 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL19452377 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL2005564 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL2005561 | 0.82 | CNR1 (0.54) | KDM4EALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL31336307 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6025511-A | A MYRISTIC ACID SELECTED ANALOGS FOR INHIBITING THE BIOSYNTHESIS OF THE GLYCOSYL PHOSPHATIDYLINOSITOL (GPI) ANCHOR OF THE PARASITE | WASHINGTON UNIVERSITY (US) | 2000-02-15 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5998642-A | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5760259-A | MYRISTIC ACID DERIVATIVES CAPABLE OF INHIBITING BIOSYNTHESIS OF PARASITE'S ANCHORING GROUP | WASHINGTON UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5747537-A | Method of inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1998-05-05 | — | — | US | disclosed |