Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | F7 | P08709 | 5/20 | 0.44 |
| ▸ | F3 | P13726 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472125 | 1.00 | HPGD (0.53) | HPGDHCAR2TBXAS1FFAR1ALDH1A1 | |
| SCHEMBL8091430 | 1.00 | HPGD (0.53) | HPGDHCAR2TBXAS1FFAR1ALDH1A1 | |
| SCHEMBL11472124 | 1.00 | HPGD (0.53) | HPGDHCAR2TBXAS1FFAR1ALDH1A1 | |
| SCHEMBL8079997 | 1.00 | HPGD (0.53) | HPGDHCAR2TBXAS1FFAR1ALDH1A1 | |
| SCHEMBL8091429 | 1.00 | HPGD (0.53) | HPGDHCAR2TBXAS1FFAR1ALDH1A1 | |
| SCHEMBL2946481 | 0.87 | HCAR2 (0.45) | HPGDHCAR2TBXAS1ALDH1A1MAPT | |
| SCHEMBL11462800 | 0.81 | HCAR2 (0.43) | HPGDHCAR2ALDH1A1MAPTLMNA | |
| SCHEMBL11462799 | 0.81 | HCAR2 (0.43) | HPGDHCAR2ALDH1A1MAPTLMNA | |
| SCHEMBL31619660 | 0.78 | NPC1 (0.59) | HPGDFFAR1ALDH1A1F7F3 | |
| SCHEMBL15688422 | 0.78 | MAPT (0.49) | HCAR2ALDH1A1MAPTLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6025511-A | A MYRISTIC ACID SELECTED ANALOGS FOR INHIBITING THE BIOSYNTHESIS OF THE GLYCOSYL PHOSPHATIDYLINOSITOL (GPI) ANCHOR OF THE PARASITE | WASHINGTON UNIVERSITY (US) | 2000-02-15 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5998642-A | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5760259-A | MYRISTIC ACID DERIVATIVES CAPABLE OF INHIBITING BIOSYNTHESIS OF PARASITE'S ANCHORING GROUP | WASHINGTON UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5747537-A | Method of inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1998-05-05 | — | — | US | disclosed |