Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854729 | 0.87 | KDM4E (0.50) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL15668326 | 0.83 | MAPT (0.67) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL646876 | 0.83 | CA12 (0.65) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL10628012 | 0.83 | TSHR (0.67) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL14513563 | 0.83 | HPGD (0.52) | MAPTTSHRKDM4EALDH1A1GAA | |
| SCHEMBL5123418 | 0.82 | CA12 (0.51) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL14032561 | 0.82 | CA12 (0.51) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL30949369 | 0.81 | CA12 (0.62) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL4959120 | 0.81 | KLKB1 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8887162 | 0.81 | CA12 (0.62) | MAPTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083987-A | 4-AMINO DERIVATIVE SUBSTITUTED PHENYLDIALKYLAMINE, USEFUL AS LIPID PEROXIDATION INHIBITOR | SHISEIDO CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |