Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426321 | 0.94 | MAPT (0.41) | MAPTKMT2ATSHRLMNANFKB1 | |
| SCHEMBL8639170 | 0.89 | MAPT (0.38) | MAPTKMT2ATSHRLMNANFKB1 | |
| SCHEMBL7196778 | 0.88 | HAO1 (0.41) | MAPTKMT2ATSHRLMNANFKB1 | |
| SCHEMBL7842197 | 0.87 | KMT2A (0.52) | MAPTKMT2ATSHRHAO1GPR84 | |
| SCHEMBL9226006 | 0.87 | MAPT (0.37) | MAPTKMT2ATSHRLMNANFKB1 | |
| SCHEMBL9228858 | 0.87 | MAPT (0.37) | MAPTKMT2ATSHRLMNANFKB1 | |
| SCHEMBL7693894 | 0.87 | KMT2A (0.64) | MAPTKMT2ATSHRHAO1GPR84 | |
| SCHEMBL7838587 | 0.87 | KMT2A (0.64) | MAPTKMT2ATSHRHAO1GPR84 | |
| SCHEMBL5276947 | 0.87 | KMT2A (0.64) | MAPTKMT2ATSHRHAO1GPR84 | |
| SCHEMBL9736541 | 0.87 | KMT2A (0.64) | MAPTKMT2ATSHRHAO1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |